A mini review on synthesis and biological activities of isatin derivatives

Mohammad Asif

Abstract


Isatin is an indole derivative and important class of heterocyclic compounds. Isatin derivatives are used for the synthesis of a large variety of heterocyclic compounds and drug synthesis. Isatin derivatives have attracted strong interest in medicinal chemistry due to their potent biological activities. Isatin and its derivatives possess various biological activities such as anticancer, antimicrobial, antiviral, anti-tubercular, anthelmintic, anti-HIV, anti-inflammatory, analgesic, antiepileptic, antioxidant and other biological activities. This review outlines some common used methods to synthesize the isatin derivatives, with advances in the use of isatin derivatives for its biological properties.


Keywords


Isatin; Antibacterial; Anticancer, Analgesic; Anti-inflammatory;Antioxidants.

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References


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